The Seveso accident: A look at 40 years of health research and beyond

Brenda Eskenazi; Marcella Warner; Paolo Brambilla; Stefano Signorini; Jennifer Ames; Paolo Mocarelli

Environment International (Dec 2018)

The Seveso accident: A look at 40 years of health research and beyond

Brenda Eskenazi,
Marcella Warner,
Paolo Brambilla,
Stefano Signorini,
Jennifer Ames,
Paolo Mocarelli

Affiliations

Brenda Eskenazi: Center for Environmental Research and Children's Health (CERCH), School of Public Health, University of California at Berkeley, Berkeley, CA, USA; Corresponding author at: Center for Environmental Research and Children's Health, School of Public Health, University of California at Berkeley, 1995 University Avenue, Suite 265, Berkeley, CA 94720-7392, USA.
Marcella Warner: Center for Environmental Research and Children's Health (CERCH), School of Public Health, University of California at Berkeley, Berkeley, CA, USA
Paolo Brambilla: Department of Laboratory Medicine, University of Milano-Bicocca, School of Medicine, Hospital of Desio, Desio-Milano, Italy
Stefano Signorini: Department of Laboratory Medicine, University of Milano-Bicocca, School of Medicine, Hospital of Desio, Desio-Milano, Italy
Jennifer Ames: Center for Environmental Research and Children's Health (CERCH), School of Public Health, University of California at Berkeley, Berkeley, CA, USA
Paolo Mocarelli: Department of Laboratory Medicine, University of Milano-Bicocca, School of Medicine, Hospital of Desio, Desio-Milano, Italy

Journal volume & issue: Vol. 121
pp. 71 – 84

Abstract

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A 1976 chemical factory explosion near Seveso, Italy exposed residents to high levels of 2,3,7,8-tetracholorodibenzo-p-dioxin (TCDD or dioxin). Dioxin is a known human carcinogen and potent endocrine disruptor. It is highly lipophilic and has a long half-life in humans. Much of what we know and can learn about the risks of dioxin exposure on human health arose from the tragic circumstances of Seveso. This review aims to describe the Seveso accident, summarize the results of 40 years of research on the health of the Seveso population since the accident, and discuss next-stage research on the health of Seveso residents, their children, and grandchildren. Keywords: Dioxin, TCDD, Seveso, Epidemiology, Disaster

Published in Environment International

ISSN: 0160-4120 (Print)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Geography. Anthropology. Recreation: Environmental sciences
Website: https://www.journals.elsevier.com/environment-international

About the journal