Nature Communications (Jun 2021)

Preventing post-surgical cardiac adhesions with a catechol-functionalized oxime hydrogel

  • Masaki Fujita,
  • Gina M. Policastro,
  • Austin Burdick,
  • Hillary T. Lam,
  • Jessica L. Ungerleider,
  • Rebecca L. Braden,
  • Diane Huang,
  • Kent G. Osborn,
  • Jeffrey H. Omens,
  • Michael M. Madani,
  • Karen L. Christman

DOI
https://doi.org/10.1038/s41467-021-24104-w
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 14

Abstract

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Postsurgical adhesions are a problem during routine cardiothoracic procedures. Here, the authors report on a catechol functionalised hydrogel as an anti-adhesion material with improved retention on the heart which is biocompatible and biodegradable with minimal swelling, demonstrating application in vivo.