Química Nova (Jan 2014)

Constituintes químicos e avaliação das atividades antioxidante e anti-inflamatória das raízes de Sabicea brasiliensis wernh (Rubiaceae)

  • Jucilene Cavalini Batista,
  • Silvana Maria de Oliveira Santin,
  • Ivânia T. Albrecht Schuquel,
  • Laura Lícia Milani de Arruda,
  • Ciomar Aparecida Bersani-Amado,
  • Cecília Maria Alves de Oliveira,
  • Lucilia Kato,
  • Heleno Dias Ferreira,
  • Cleuza Conceição da Silva

DOI
https://doi.org/10.5935/0100-4042.20140095
Journal volume & issue
Vol. 37, no. 4
pp. 638 – 642

Abstract

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The phytochemical investigation of Sabicea brasiliensis roots led to the isolation of 5-O-caffeoylquinic acid, 3,5- and 4,5-O-dicaffeoylquinics acids, scopoletin, ursolic acid, a mixture of β-sitosterol, stigmasterol and campesterol, daucosterol and saccharose. The structures of the isolated compounds were assigned on the basis of one- and two-dimensional NMR spectroscopic methods and by comparison with literature data. The anti-inflammatory and antioxidant activities of the crude methanolic extract and its fractions were analyzed.

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