Nature Communications (Feb 2019)
Highly efficient photothermal nanoagent achieved by harvesting energy via excited-state intramolecular motion within nanoparticles
- Zheng Zhao,
- Chao Chen,
- Wenting Wu,
- Fenfen Wang,
- Lili Du,
- Xiaoyan Zhang,
- Yu Xiong,
- Xuewen He,
- Yuanjing Cai,
- Ryan T. K. Kwok,
- Jacky W. Y. Lam,
- Xike Gao,
- Pingchuan Sun,
- David Lee Phillips,
- Dan Ding,
- Ben Zhong Tang
Affiliations
- Zheng Zhao
- Department of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute of Molecular Functional Materials, Division of Life Science and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology
- Chao Chen
- State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Sciences, Nankai University
- Wenting Wu
- Key Laboratory of Synthetic and Self-assembly Chemistry for Organic Functional Molecules, Shanghai Institute of Organic Chemistry, Chinese Academy of Science
- Fenfen Wang
- Key Laboratory of Functional Polymer Materials, Ministry of Education, College of Chemistry, Nankai University
- Lili Du
- Department of Chemistry, The University of Hong Kong
- Xiaoyan Zhang
- State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Sciences, Nankai University
- Yu Xiong
- Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, Shenzhen Research Institute
- Xuewen He
- Department of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute of Molecular Functional Materials, Division of Life Science and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology
- Yuanjing Cai
- Department of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute of Molecular Functional Materials, Division of Life Science and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology
- Ryan T. K. Kwok
- Department of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute of Molecular Functional Materials, Division of Life Science and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology
- Jacky W. Y. Lam
- Department of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute of Molecular Functional Materials, Division of Life Science and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology
- Xike Gao
- Key Laboratory of Synthetic and Self-assembly Chemistry for Organic Functional Molecules, Shanghai Institute of Organic Chemistry, Chinese Academy of Science
- Pingchuan Sun
- Key Laboratory of Functional Polymer Materials, Ministry of Education, College of Chemistry, Nankai University
- David Lee Phillips
- Department of Chemistry, The University of Hong Kong
- Dan Ding
- State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Sciences, Nankai University
- Ben Zhong Tang
- Department of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute of Molecular Functional Materials, Division of Life Science and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology
- DOI
- https://doi.org/10.1038/s41467-019-08722-z
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 11
Abstract
Molecular motion has attracted a wide range of interest for different applications. Here, the authors develop nanoparticles with internal molecular motion upon near infrared absorption and use the nanoparticles for photoacoustic imaging and demonstrate this application in vivo.
