SNP based analysis depicts phenotypic variability in heme oxygenase-1 protein

Abstract

The heme oxygenase-1 (HMOX1) gene is a very critical player in cell homeostasis and takes part in heme catabolism. The HMOX1 gene possesses antioxidant, antiapoptotic anti-inflammatory, and antithrombotic properties. This study aimed to identify the deleterious SNPs which may alter the functional and structural attributes of the HMOX1 protein.

Keywords

• deleterious
• mutation
• non-synonymous
• protein function
• snps