Journal of the Korean Society of Radiology (Jul 2024)

Mucin-Rich Brain Metastasis May Show the T2-FLAIR Mismatch Sign: A Case Report and Literature Review

  • Hyun Jae Kim,
  • Yoon Jin Cha,
  • Seung Ho Choi,
  • Chang Joon Kang,
  • Jihwan Yoo,
  • Sung Jun Ahn

Journal volume & issue
Vol. 85, no. 4
pp. 758 – 788

Abstract

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This study describes a unique case of single mucin-rich brain metastasis in a patient with breast cancer, mimicking the T2-fluid attenuation inversion recovery (FLAIR) mismatch sign and masquerading as an isocitrate dehydrogenase-mutant astrocytoma. This case highlights the importance of considering mucin-rich lesions in the differential diagnosis of intracranial tumors exhibiting T2-FLAIR mismatch. Clinicians must recognize the potential convergence in imaging characteristics between these metastases and gliomas to guarantee prompt and accurate patient care.

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