<b>Efficient sodium selenate-catalyzed synthesis of 3,4-dihydro-2(1<i>H</i>)-pyrimidinones and –thiones under solvent-free conditions</b>

Abstract

Sodium selenate efficiently catalyzes the three-component Biginelli reaction of an aldehyde, a,β-keto ester and urea or thiourea under solvent-free conditions to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones or –thiones in excellent yields.

Keywords

• Dihydropyrimidinones
• Sodium selenate
• Biginelli reaction
• Three component reaction