A concise and efficient synthesis of benzimidazo[1,2-c]quinazolines through CuI-catalyzed intramolecular N-arylations

Abstract

A series of functionalized benzimidazo[1,2-c]quinazoline derivatives was obtained in excellent yields under mild conditions through a CuI-catalyzed Ullmann N-arylation starting from easily available starting materials.

Keywords

• benzimidazo[1,2-c]quinazoline
• (bromophenyl)iodonium salt
• copper catalyst
• o-cyanoaniline
• quinazolin-4(3H)-imine
• Ullmann N-arylation