Nature Communications (Jun 2017)

Discovery of long-range inhibitory signaling to ensure single axon formation

  • Tetsuya Takano,
  • Mengya Wu,
  • Shinichi Nakamuta,
  • Honda Naoki,
  • Naruki Ishizawa,
  • Takashi Namba,
  • Takashi Watanabe,
  • Chundi Xu,
  • Tomonari Hamaguchi,
  • Yoshimitsu Yura,
  • Mutsuki Amano,
  • Klaus M. Hahn,
  • Kozo Kaibuchi

DOI
https://doi.org/10.1038/s41467-017-00044-2
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 18

Abstract

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Emerging evidence suggests that gut microbiota influences immune function in the brain and may play a role in neurological diseases. Here, the authors offer in vivo evidence from a Drosophila model that supports a role for gut microbiota in modulating the progression of Alzheimer’s disease.