Опухоли головы и шеи (Apr 2017)

ANALYSIS RESULTS OF COMBINED TREATMENT OF PATIENTS WITH VERIFIED CANCER OF THE CERVICAL ESOPHAGUS AND HYPOPHARYNX WITH THE APPLICATION OF SURGICAL TREATMENT WITH ONE-STAGE DEFECT’S PLASTIC

  • Z. A. Radzhabova,
  • E. V. Levchenko,
  • I. V. Dunaevskiy,
  • L. V. Gorokhov,
  • M. A. Kotov,
  • N. V. Khandogin,
  • D. А. Rakitina,
  • R. А. Nazhmudinov,
  • M. M. Girshovich,
  • E. I. Tyuryaeva,
  • E. V. Tkachenko,
  • О. I. Ponomareva

DOI
https://doi.org/10.17650/2222-1468-2016-6-4-11-14
Journal volume & issue
Vol. 6, no. 4
pp. 11 – 14

Abstract

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In the treatment of many unresolved issues, indicating the need for research aimed at finding more effective treatment approaches. The aim of the study is to analyze the results of combined treatment of patients with widespread forms of cancer of the cervical esophagus and hypopharynx with the application of surgical treatment in the amount of pharyngolaryngitis with single-step plastic of the defect. A retrospective analysis of results of combined treatment of 28 patients with a verified diagnosis of cancer of the cervical esophagus and hypopharynx. Combined treatment of patients with cancer of the cervical esophagus and hypopharynx included the following treatments: induction chemoradiotherapy according to the scheme cisplatin/5-fluorouracil, external beam radiation therapy 65 Gy, brachytherapy (7 Gy 1 time per week, 3 sessions), surgical treatment with one-stage plastic of the esophagus. In 7 patients (25 %) was achieved complete regression on the background of induction chemotherapy, 21 patients (75 %) received the treatment in full. Postoperative mortality rate was of 9.52 %, post-operative complications such as anastomosis dehiscence – 19 %.

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