A multiplex chemiluminescent immunoassay for serological profiling of COVID-19-positive symptomatic and asymptomatic patients

Allison N. Grossberg; Lilia A. Koza; Aurélie Ledreux; Chad Prusmack; Hari Krishnan Krishnamurthy; Vasanth Jayaraman; Ann-Charlotte Granholm; Daniel A. Linseman

doi:10.1038/s41467-021-21040-7

Nature Communications (Feb 2021)

A multiplex chemiluminescent immunoassay for serological profiling of COVID-19-positive symptomatic and asymptomatic patients

Allison N. Grossberg,
Lilia A. Koza,
Aurélie Ledreux,
Chad Prusmack,
Hari Krishnan Krishnamurthy,
Vasanth Jayaraman,
Ann-Charlotte Granholm,
Daniel A. Linseman

Affiliations

Allison N. Grossberg: Knoebel Institute for Healthy Aging, University of Denver
Lilia A. Koza: Knoebel Institute for Healthy Aging, University of Denver
Aurélie Ledreux: Knoebel Institute for Healthy Aging, University of Denver
Chad Prusmack: Resilience Code
Hari Krishnan Krishnamurthy: Vibrant Sciences LLC
Vasanth Jayaraman: Vibrant Sciences LLC
Ann-Charlotte Granholm: Knoebel Institute for Healthy Aging, University of Denver
Daniel A. Linseman: Knoebel Institute for Healthy Aging, University of Denver

DOI: https://doi.org/10.1038/s41467-021-21040-7
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 11

Abstract

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Antibody responses to SARS-CoV-2 may be important biomarkers for assessing the risk for viral transmission. Here the authors present serological antibody profiling results of COVID-19 patients using a new multiplex assay to show distinct kinetics and dynamics of IgG, IgM and IgA responses in patients with different disease severity.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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