Research progress on the use of Salvia miltiorrhiza Bunge extracts in the treatment of pulmonary diseases

Peifeng Huang; Xuezhen Wang; Yingyi Cao; Jiaming Yang; Rongmei Yao; Leiqin Liang; Gong Cheng; Long Yang

Biomedicine & Pharmacotherapy (Oct 2024)

Research progress on the use of Salvia miltiorrhiza Bunge extracts in the treatment of pulmonary diseases

Peifeng Huang,
Xuezhen Wang,
Yingyi Cao,
Jiaming Yang,
Rongmei Yao,
Leiqin Liang,
Gong Cheng,
Long Yang

Affiliations

Peifeng Huang: School of Integrative medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Xuezhen Wang: School of Integrative medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Yingyi Cao: New Cornerstone Science Laboratory, Tsinghua University-Peking University Joint Center for Life Sciences, School of Basic Medical Sciences, Tsinghua University, Beijing 100084, China
Jiaming Yang: Research Center for Infectious Diseases, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Rongmei Yao: Research Center for Infectious Diseases, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Leiqin Liang: Research Center for Infectious Diseases, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; Corresponding author.
Gong Cheng: New Cornerstone Science Laboratory, Tsinghua University-Peking University Joint Center for Life Sciences, School of Basic Medical Sciences, Tsinghua University, Beijing 100084, China; Institute of Infectious Diseases, Shenzhen Bay Laboratory, Shenzhen, Guangdong 518000, China; Corresponding author at: New Cornerstone Science Laboratory, Tsinghua University-Peking University Joint Center for Life Sciences, School of Basic Medical Sciences, Tsinghua University, Beijing 100084, China.
Long Yang: School of Integrative medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; Research Center for Infectious Diseases, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; Corresponding author at: School of Integrative medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.

Journal volume & issue: Vol. 179
p. 117282

Abstract

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Salvia miltiorrhiza Bunge extracts, known for their diverse biological activities, often have remarkable efficacy in treating pulmonary diseases overlooked due to their specific cardiovascular actions. With the recent outbreak of COVID-19, research into pulmonary-related diseases has garnered significant attention. Salvia miltiorrhiza Bunge extracts can be broadly categorized into lipophilic and hydrophilic components; however, a comprehensive summary of their mechanisms in treating pulmonary diseases is lacking. Therefore, this review aims to systematically summarize the therapeutic mechanisms of 10 major Salvia miltiorrhiza Bunge extracts in treating pulmonary fibrosis, lung cancer, acute lung injury, and chronic obstructive pulmonary disease, with the goal of identifying promising options for efficacious therapies.

Published in Biomedicine & Pharmacotherapy

ISSN: 0753-3322 (Print); 1950-6007 (Online)
Publisher: Elsevier
Country of publisher: France
LCC subjects: Medicine: Therapeutics. Pharmacology
Website: https://www.journals.elsevier.com/biomedicine-and-pharmacotherapy

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