Gynecology Obstetrics & Reproductive Medicine (Dec 2008)

Prenatally Diagnosed Ureteropelvic Junction Obstruction in Three Siblings of one Family: A Case Report

  • Sinan Beksaç,
  • Sevim Balcı,
  • Zuhal Yapıcı,
  • Özgür Özyüncü

Journal volume & issue
Vol. 14, no. 3

Abstract

Read online

Ureteropelvic junction obstruction is a rare congenital abnormality. The mode of inheritance is thought to be autosomal dominant with variable expressivity. Here, a consanguineous family whose three siblings diagnosed to have various degree of ureteropelvic junction obstruction is presented. Ureteropelvic junction obstruction may have a genetic background and may recur in subsequent pregnancies. Furthermore, genetic thrombophilias may be associated with urinary abnormalities. Further molecular studies are necessary to prove that finding.

Keywords