A Five-year Follow-up Study on Elderly Patients with Fragility Fractures

Abstract

Objective To understand the refracture and mortality rate of elderly patients with fragility fractures within 5 years,and in order to identify relevant influencing factors. Methods A retrospective analysis was conducted on 775 elderly patients with brittle fractures admitted to the Orthopedics Department of the Second Affiliated Hospital of Dalian Medical University from January 2015 to December 2016.The patient's refracture and death rates within 5 years were analyzed through telephone consultation combined with the hospital′s electronic medical record system.The impact of refracture and death was analyzed using a Cox risk ratio model. Results 634 patients were effectively followed up within 5 years,with an overall refracture rate of 16.25%(103 cases) and a mortality rate of 32.97%(209 cases) within 5 years.Cox multiple regression analysis showed that age,first vertebral fracture were independent risk factors for refracture(P<0.05),while the use of anti-osteoporosis drugs,calcium supplements and/or vitamin D,and blood creatinine levels were protective factors for refracture(P<0.05);Age,male,and fasting blood glucose were independent risk factors for death(P<0.05),while body mass index,albumin,limb fracture as the first fracture site,taking anti-osteoporosis drugs,calcium supplements,and/or vitamin D were protective factors for death(P<0.05). Conclusion Elderly patients with fragility fractures have a higher rate of refracture and mortality within 5 years.Age,site of first fracture,use of anti-osteoporosis drugs,and use of calcium and/or vitamin D have an impact on refracture and mortality.

Keywords

• fragility fracture in the elderly
• refracture rate
• mortality rate