The Research of Preparation Process of Tungsten Oxide with Enriched 186W Isotope

Abstract

Enriched tungsten-186 oxide is one of the stable isotope products of tungsten. It is used to prepare the radioactive medical isotope product 188WO3, which can be used as the target material of 188W/188Re generator to produce medical 188Re isotope product, so as to meet the increasing requirements of biomedical markers, bone cancer treatment and other medical related fields. In order to satisfy the current market demand for 186WO3, the preparation process of 186WO3 with tungsten-186 hexafluoride (186WF6) as the raw material was studied and determined. The key parameters of preparation processes were systematically optimized, and the influence of essential parameters on the 186WO3 product purity and process yield was obtained, which determined the optimal process parameters. Finally, the high conversion rate process route was achieved, and the enriched 186WO3 products were obtained. The chemical purity of 186WO3 can reach 99.91%-99.93% with the process yield of 89.8%-90.5% under the optimal process conditions. The research consequences of this article can provide a theoretical and experimental basis for the batch preparation of 186WO3, and give the technical reference for the process of preparing metal oxides from other similar gas-phase fluorides.

Keywords

• tungsten-186 oxide
• tungsten-186 hexafluoride
• preparation route
• process parameter