Acta Biomedica Scientifica (Nov 2014)

ANTIOXIDANT ACTIVITY OF THE DRY EXTRACT RHAPONTICUM UNIFLORUM (L.) DC

  • N. K. Tatarinova,
  • I. V. Sviridov,
  • A. A. Toropova,
  • L. N. Shantanova,
  • L. L. Garmayeva

Journal volume & issue
Vol. 0, no. 6
pp. 52 – 54

Abstract

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A study of the antioxidant activity of the in vitro dry extracts DER-1 and DER-2 derived from Rhaponticum uniflorum (L.) DC. It was established that the extracts have pronounced antiradical activity against DPPH-radical binding (IC50 (DER-2) = 2.0 mkg/ml). When studying the effect of the dry extracts a number of reactive oxygen species (O•-2, NO) revealed that they exhibit their ability to inactivate. With respect to Of-anion radical extracts show moderate and against NO - expressed antiradical activity (IC50 (DER-2) = 311.0 mkg/ml). We also revealed the presence of moderate Fe2+-chelating activity of the extracts studied. This effect is caused by apparently content of phenolic compounds, phenol carbonic acids, triterpene saponins and tannins.

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