Phytochemical Compounds and Pharmacological Properties of <i>Larrea tridentata</i>
Ana Lizet Morales-Ubaldo,
Nallely Rivero-Perez,
Benjamín Valladares-Carranza,
Alfredo Madariaga-Navarrete,
Rosa Isabel Higuera-Piedrahita,
Lucía Delgadillo-Ruiz,
Rómulo Bañuelos-Valenzuela,
Adrian Zaragoza-Bastida
Affiliations
Ana Lizet Morales-Ubaldo
Área Académica de Medicina Veterinaria y Zootecnia, Instituto de Ciencias Agropecuarias, Universidad Autónoma del Estado de Hidalgo, Rancho Universitario Av. Universidad km 1, EX-Hda de Aquetzalpa, Tulancingo 43600, Hidalgo, Mexico
Nallely Rivero-Perez
Área Académica de Medicina Veterinaria y Zootecnia, Instituto de Ciencias Agropecuarias, Universidad Autónoma del Estado de Hidalgo, Rancho Universitario Av. Universidad km 1, EX-Hda de Aquetzalpa, Tulancingo 43600, Hidalgo, Mexico
Benjamín Valladares-Carranza
Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, El Cerrillo Piedras Blancas, Toluca 50090, Estado de Mexico, Mexico
Alfredo Madariaga-Navarrete
Área Académica de Ciencias Agrícolas y Forestales, Universidad Autónoma del Estado de Hidalgo, Instituto de Ciencias Agropecuarias, Rancho Universitario Av. Universidad km 1, EX-Hda de Aquetzalpa, Tulancingo 43600, Hidalgo, Mexico
Rosa Isabel Higuera-Piedrahita
Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Carretera Cuautitlán-Teoloyucan km 2.5, San Sebastián Xhala, Cuautitlán 54714, Estado de Mexico, Mexico
Lucía Delgadillo-Ruiz
Unidad Académica de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Zacatecas, Kilómetro 31.5 Carretera Panamerica, Fresnillo 98500, Zacatecas, Mexico
Rómulo Bañuelos-Valenzuela
Unidad Académica de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Zacatecas, Kilómetro 31.5 Carretera Panamerica, Fresnillo 98500, Zacatecas, Mexico
Adrian Zaragoza-Bastida
Área Académica de Medicina Veterinaria y Zootecnia, Instituto de Ciencias Agropecuarias, Universidad Autónoma del Estado de Hidalgo, Rancho Universitario Av. Universidad km 1, EX-Hda de Aquetzalpa, Tulancingo 43600, Hidalgo, Mexico
For centuries, traditional medicine from plants (phytotherapy) was the only treatment for infectious and non-infectious diseases. Although it is still practiced in several countries with excellent therapeutic results, it is frequently underestimated because, unlike Western medicine, it is not based on an empirical scientific foundation. However, interest in the search for plant-based therapeutic resources has been stimulated by disciplines such as phytochemistry and the side effects of conventional pharmacological therapies. For example, Larrea tridentata is a perennial shrub used in traditional medicine in northern Mexico and the southern United States to treat infertility, rheumatism, arthritis, colds, diarrhea, skin problems, pain, inflammation and excess body weight. Scientific research has revealed its beneficial effects—antioxidant, antitumor, neuroprotective, regenerative, antibacterial, antiviral, antifungal, anthelmintic, antiprotozoal and insecticidal—although reports indicate that some compounds in Larrea tridentata may be hepatotoxic and nephrotoxic. Therefore, the aim of this review was to highlight the updates regarding phytochemical compounds and the pharmacological properties of Larrea tridentata.
