Nature Communications (Dec 2016)
Atomic structure of the innexin-6 gap junction channel determined by cryo-EM
Abstract
Gap junctions have critical roles in maintaining homeostasis in multicellular organisms. Here the authors present cryo-EM structures of the C. elegansinnexin-6 gap junction channel, revealing high structural similarity to human connexin 26 despite a different oligomeric number and lack of sequence similarity.