The study focuses on the artificial intelligence empowered road vehicle- train collision risk prediction assessment, which may lead to the development of a road vehicle-train collision avoidance system for unmanned railway level crossings. The study delimits itself around the road vehicle-train collisions at unmanned railway level crossings on single line rail-road sections. The first objective of the study revolves around the rail-road collision risk evaluation by the development of road vehicle-train collision frequency and severity prediction model using Poisson and Gamma-log regression techniques respectively. Another study objective is the collision modification factor implementation on predicted risk factors, to reduce the road vehicle-train collision risk at the crossings. The collision risk has been predicted to be 3.52 times higher and 77% lower in one direction while in other directions it is 2.95 times higher and 80% lower than average risk at all unmanned railway level crossings. With collision modification factor application on higher risk contributing factors i.e. `crossing angle' and `train visibility, it predicts to reduce the road vehicle-train collision risk to 85% approximately.