Hereditary Neuropathy with liability to Pressure Palsies revealed by a Chronic Inflammatory Demyelinating Polyradiculoneuropathy. A case report and literature review

Abstract

Introduction - Hereditaryneuropathy with liability to pressure palsies is a sensory-motorneuropathy with autosomal dominant inheritance linked to a deletion ofthe PMP22 gene on chromosome 17p11.2. Its association with acquired dysimmuneneuropathy such as chronic inflammatory demyelinating polyradiculoneuropathyis rare. Observation - We report the case of a 31-years-old patient, who experienced a multifocal and painful chronic inflammatory demyelinating polyradiculoneuropathy, eignt weeks after surgery for a right carpal tunnel syndrome. The patient had no clinical signs suggestive of hereditary neuropathy with liability to pressure palsies but the electroneuromyography referred us to this neuropathy and the genetic analysis confirmed the PMP22 deletion.

Keywords

• Hereditary Neuropathy with Liability to Pressure Palsy HNPP
• chronic inflammatory demyelinating polyradiculoneuropathy CIDP
• carpal tunnel syndrome