Mutations of TP53 gene in adult acute lymphoblastic leukemia at diagnosis do not affect the achievement of hematologic response but correlate with early relapse and very poor survival

• Silvia Salmoiraghi,
• Marie Lorena Guinea Montalvo,
• Greta Ubiali,
• Manuela Tosi,
• Barbara Peruta,
• Pamela Zanghi,
• Elena Oldani,
• Cristina Boschini,
• Alexander Kohlmann,
• Silvia Bungaro,
• Tamara Intermesoli,
• Elisabetta Terruzzi,
• Emanuele Angelucci,
• Irene Cavattoni,
• Fabio Ciceri,
• Renato Bassan,
• Alessandro Rambaldi,
• Orietta Spinelli

Affiliations

Silvia Salmoiraghi

Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy

Marie Lorena Guinea Montalvo

Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy

Greta Ubiali

Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy

Manuela Tosi

Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy

Barbara Peruta

Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy

Pamela Zanghi

Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy

Elena Oldani

Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy

Cristina Boschini

Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy

Alexander Kohlmann

Personalized Healthcare and Biomarkers, Innovative Medicines and Early Development, AstraZeneca, Cambridge, UK

Silvia Bungaro

Centro Ricerche Tettamanti, Clinica Pediatrica Università Milano-Bicocca, Ospedale San Gerardo, Monza, Italy

Tamara Intermesoli

Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy

Elisabetta Terruzzi

Divisione di Ematologia e Trapianto di Midollo Osseo, Ospedale San Gerardo, Monza, Italy

Emanuele Angelucci

Ematologia e Centro Trapianti, Ospedale Oncologico di Riferimento Regionale “Armando Businco”, Azienda Ospedaliera “Brotzu”, Cagliari, Italy

Irene Cavattoni

Ematologia e Centro Trapianti di Midollo Osseo, Ospedale Centrale, Bolzano, Italy

Fabio Ciceri

Hematology, IRCCS San Raffaele Scientific Institute, Milano, Italy

Renato Bassan

Hematology, Ospedale dell’Angelo, Mestre-Venezia, Italy

Alessandro Rambaldi

Dipartimento Scienze Cliniche e di Comunità, University of Milan, Italy;Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy

Orietta Spinelli

Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy