Involvement of Asc and Nlrp3 inflammasomes in the testes following spinal cord injury

Ramezanikhah Hajar; Farrokhi Ahmad; Nejatbakhsh Reza; Shokri Saeed; Zendedel Adib; Abdanipour Alireza

doi:10.2478/enr-2020-0012

Endocrine Regulations (Apr 2020)

Involvement of Asc and Nlrp3 inflammasomes in the testes following spinal cord injury

Ramezanikhah Hajar,
Farrokhi Ahmad,
Nejatbakhsh Reza,
Shokri Saeed,
Zendedel Adib,
Abdanipour Alireza

Affiliations

Ramezanikhah Hajar: Department of Anatomical Sciences, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
Farrokhi Ahmad: Department of Anatomical Sciences, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
Nejatbakhsh Reza: Department of Anatomical Sciences, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
Shokri Saeed: Department of Anatomical Sciences, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
Zendedel Adib: Institute of Neuroanatomy, Faculty of Medicine, RWTH Aachen University, Aachen, Germany
Abdanipour Alireza: Department of Anatomical Sciences, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran

DOI: https://doi.org/10.2478/enr-2020-0012
Journal volume & issue: Vol. 54, no. 2
pp. 96 – 108

Abstract

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Objective. The exact mechanism, by which spinal cord injury (SCI) leads to a male subfertility is not well-known. Present study was conducted to determine the mechanisms that lead to the elevated end-product cytokines and inflammasomes in the testes of an SCI rat model. Moreover, we evaluated the inflammasome components following SCI in testis over a defined time periods.

Published in Endocrine Regulations

ISSN: 1336-0329 (Online)
Publisher: Sciendo
Country of publisher: Poland
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology
Website: https://sciendo.com/journal/ENR

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