Dexamethasone treatment for COVID-19 is related to increased mortality in hematologic malignancy patients: results from the EPICOVIDEHA Registry

• Tommaso Francesco Aiello,
• Jon Salmanton-Garcia,
• Francesco Marchesi,
• Barbora Weinbergerova,
• Andreas Glenthoj,
• Jens Van Praet,
• Francesca Farina,
• Julio Davila-Valls,
• Sonia Martin-Perez,
• Shaimaa El-Ashwah,
• Martin Schonlein,
• Iker Falces-Romero,
• Jorge Labrador,
• Uluhan Sili,
• Caterina Buquicchio,
• Antonio Vena,
• Gaetan Plantefeve,
• Verena Petzer,
• Monika M. Biernat,
• Tobias Lahmer,
• Ildefonso Espigado,
• Jaap Van Doesum,
• Ola Blennow,
• Klara Piukovics,
• Carlo Tascini,
• Michail Samarkos,
• Yavuz M. Bilgin,
• Luana Fianchi,
• Federico Itri,
• Toni Valković,
• Nicola S. Fracchiolla,
• Michelina Dargenio,
• Moraima Jimenez,
• Ferenc Magyari,
• Alberto Lopez-Garcia,
• Lucia Prezioso,
• Natasha Čolović,
• Evgenii Shumilov,
• Ghaith Abu-Zeinah,
• Carolin Krekeler,
• Esperanza Lavilla-Rubira,
• Mario Virgilio Papa,
• Tomas Jose Gonzalez-Lopez,
• Laszlo Imre Pinczes,
• Fatih Demirkan,
• Natasha Ali,
• Caroline Besson,
• Guillemette Fouquet,
• Alessandra Romano,
• Jose-Angel Hernandez-Rivas,
• Maria Ilaria Del Principe,
• Avinash Aujayeb,
• Maria Merelli,
• Sylvain Lamure,
• Joyce Marques De Almeida,
• Maria Gomes Da Silva,
• Noha Eisa,
• Joseph Meletiadis,
• Ikhwan Rinaldi,
• Olimpia Finizio,
• Ozren Jaksic,
• Mario Delia,
• Summiya Nizamuddin,
• Monia Marchetti,
• Marriyam Ijaz,
• Marina Machado,
• Rebeca Bailen-Almorox,
• Martin Čerňan,
• Nicola Coppola,
• Eleni Gavriilaki,
• Chiara Cattaneo,
• Ana Groh,
• Zlate Stojanoski,
• Nurettin Erben,
• Nicola Pantic,
• Gustavo-Adolfo Mendez,
• Roberta Di Blasi,
• Stef Meers,
• Cristina De Ramon,
• Nathan C. Bahr,
• Ziad Emarah,
• Gina Varricchio,
• Milche Cvetanoski,
• Ramon Garcia-Sanz,
• Mirjana Mitrovic,
• Raphael Lievin,
• Michaela Hanakova,
• Zdeněk Račil,
• Maria Vehreschild,
• Athanasios Tragiannidis,
• Raquel Nunes Rodrigues,
• Daniel Garcia-Bordallo,
• Raul Cordoba,
• Alba Cabirta,
• Anna Nordlander,
• Emanuele Ammatuna,
• Elena Arellano,
• Dominik Wolf,
• Romane Prin,
• Alessandro Limongelli,
• Martina Bavastro,
• Gokce Melis Colak,
• Stefanie Grafe,
• Ditte Stampe Hersby,
• Laman Rahimli,
• Oliver A. Cornely,
• Carolina Garcia-Vidal,
• Livio Pagano,
• EPICOVIDEHA study group

Affiliations

Tommaso Francesco Aiello

Infectious Diseases Department, Hospital Clinic of Barcelona-IDIBAPS, Universitat de Barcelona, Barcelona

Jon Salmanton-Garcia

University of Cologne, Faculty of Medicine and University Hospital Cologne, Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne

Francesco Marchesi

Hematology and Stem Cell Transplant Unit, IRCCS Regina Elena National Cancer Institute, Rome

Barbora Weinbergerova

Department of Internal Medicine - Hematology and Oncology, Masaryk University Hospital Brno, Brno, Czech Republic

Andreas Glenthoj

Department of Hematology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark

Jens Van Praet

Department of Nephrology and Infectious diseases, AZ Sint-Jan Brugge-Oostende AV, Brugge

Francesca Farina

IRCCS Ospedale San Raffaele, Milan

Julio Davila-Valls

Hospital Nuestra Senora de Sonsoles, Avila

Sonia Martin-Perez

Hospital Nuestra Senora de Sonsoles, Avila

Shaimaa El-Ashwah

Oncology Center, Mansoura University, Mansoura, Egypt

Martin Schonlein

Department of Oncology, Hematology and Bone Marrow Transplantation with Section of Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg

Iker Falces-Romero

La Paz University Hospital, Madrid, Spain; CIBERINFEC, Instituto de Salud Carlos III, Madrid

Jorge Labrador

Department of Hematology, Research Unit, Hospital Universitario de Burgos, Burgos

Uluhan Sili

Department of Infectious Diseases and Clinical Microbiology, School of Medicine, Marmara University, Istanbul

Caterina Buquicchio

Haematology Dept., Dimiccoli Hospital, Barletta

Antonio Vena

Ospedale San Martino, Genova

Gaetan Plantefeve

Centre Hospitalier d'Argenteuil, Argenteuil

Verena Petzer

Department of Hematology and Oncology, Medical University of Innsbruck, Innsbruck, Austria

Monika M. Biernat

Department of Haematology, Blood Neoplasms, and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland

Tobias Lahmer

Medizinische Klinik II, Klinikum rechts der Isar, TU Munchen, Munich

Ildefonso Espigado

Department of Hematology, University Hospital Virgen Macarena - University Hospital Virgen del Rocio, Instituto de Biomedicina de Sevilla (IBIS / CSIC), Universidad de Sevilla, Seville

Jaap Van Doesum

University Medical Center Groningen, Groningen

Ola Blennow

Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden

Klara Piukovics

Department of Internal Medicine, South Division Faculty of Medicine University of Szeged, Szeged, Hungary

Carlo Tascini

Azienda Sanitaria Universitaria del Friuli Centrale, Udine

Michail Samarkos

Laikon Hospital, Athens, Greece

Yavuz M. Bilgin

Department of Internal Medicine, ADRZ, Goes

Luana Fianchi

Hematology Unit, Fondazione Policlinico Universitario Agostino Gemelli - IRCCS, Rome

Federico Itri

San Luigi Gonzaga Hospital - Orbassano, Orbassano

Toni Valković

University Hospital Centre Rijeka, Rijeka, Croatia; Croatian Cooperative Group for Hematological Diseases (CROHEM) Faculty of Medicine and Faculty of Health Studies University of Rijeka, Rijeka, Croatia

Nicola S. Fracchiolla

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan

Michelina Dargenio

Hematology and Stem Cell transplant Unit, Vito Fazzi, Lecce

Moraima Jimenez

Department of Hematology, Vall d’Hebron Hospital Universitari, Experimental Hematology, Vall d’Hebron Institute of Oncology (VHIO), Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain; Departament de Medicina, Universitat Autonoma de Barcelona, Bellaterra

Ferenc Magyari

Division of Hematology, Institution of Internal Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary

Alberto Lopez-Garcia

Fundacion Jimenez Diaz University Hospital, Health Research Institute IIS-FJD, Madrid

Lucia Prezioso

Hospital University of Parma - Hematology and Bone Marrow Unit, Parma

Natasha Čolović

University Clinical Center Serbia, Medical Faculty University Belgrade, Belgrade, Serbia

Evgenii Shumilov

UK Munster, Munster

Ghaith Abu-Zeinah

Division of Hematology and Oncology, Weill Cornell Medicine, New York

Carolin Krekeler

Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Munster (UKM), Munster

Esperanza Lavilla-Rubira

Hospital Lucus Augusti, Lugo

Mario Virgilio Papa

Azienda Ospedaliera Sant'Anna e San Sebastiano, Caserta

Tomas Jose Gonzalez-Lopez

Department of Hematology, Hospital Universitario de Burgos, Burgos

Laszlo Imre Pinczes

Division of Hematology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary

Fatih Demirkan

Dokuz Eylul University, Division of Hematology, Izmir

Natasha Ali

Aga Khan University, Karachi

Caroline Besson

Centre Hospitalier de Versailles, Le Chesnay, France; Universite Paris-Saclay, UVSQ, Inserm, Equipe "Exposome et Heredite", CESP, Villejuif

Guillemette Fouquet

Department of Hematology, CH Sud Francilien, Corbeil Essonnes

Alessandra Romano

Divisione Clinicizzata di Ematologia, Ospedale Ferrarotto, Catania

Jose-Angel Hernandez-Rivas

Hospital Universitario Infanta Leonor, Madrid

Maria Ilaria Del Principe

Hematology, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome

Avinash Aujayeb

Northumbria Healthcare, Newcastle

Maria Merelli

Azienda Sanitaria Universitaria del Friuli Centrale, Udine

Sylvain Lamure

Department of Clinical Hematology, Montpellier University Hospital, IGMM UMR5535 CNRS, University of Montpellier, Montpellier

Joyce Marques De Almeida

Istituto Oncologico della Svizzera Italiana, Bellinzona, Switzerland

Maria Gomes Da Silva

Portuguese Institute of Oncology, Lisbon

Noha Eisa

Aseer Central Hospital, Abha

Joseph Meletiadis

Clinical Microbiology Laboratory, Medical School, "Attikon" University General Hospital, National and Kapodistrian University of Athens, Athens, Greece

Ikhwan Rinaldi

Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia

Olimpia Finizio

UOC Hematology, AORN Cardarelli, Naples

Ozren Jaksic

Department of Hematology, University Hospital Dubrava, Zagreb, Croatia

Mario Delia

Hematology and Stem Cell Transplantation Unit, AOUC Policlinico, Bari

Summiya Nizamuddin

Memorial Cancer Hospital and Research Centre, Lahore

Monia Marchetti

Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo, Alessandria

Marriyam Ijaz

Memorial Cancer Hospital and Research Centre, Lahore

Marina Machado

Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Maranon, Madrid

Rebeca Bailen-Almorox

Hematology Department, Hospital General Universitario Gregorio Maranon, Madrid

Martin Čerňan

Department of Hemato-Oncology, Faculty of Medicine and Dentistry, Palacky University and University Hospital Olomouc, Olomouc, Czech Republic

Nicola Coppola

Department of Mental Health and Public Medicine, University of Campania, Naples

Eleni Gavriilaki

General Hospital of Thessaloniki "George Papanikolaou", Thessaloniki, Greece

Chiara Cattaneo

Hematology Unit, ASST-Ospedali Civili, Brescia

Ana Groh

Infektiologie, Universitatsklinikum Frankfurt am Main, Frankfurt am Main

Zlate Stojanoski

University Clinic of Hematology, Skopje, North Macedonia

Nurettin Erben

Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine Eskisehir Osmangazi University, Eskisehir

Nicola Pantic

University Clinical Center Serbia, Medical Faculty University Belgrade, Belgrade, Serbia

Gustavo-Adolfo Mendez

Hospital Escuela de Agudos Dr. Ramon Madariaga, Posadas

Roberta Di Blasi

Service d’Hematologie-Oncologie, Hopital St Louis, Assistance Publique - Hopitaux de Paris; Universite de Paris Diderot, Paris

Stef Meers

AZ KLINA, Brasschaat

Cristina De Ramon

Hematology Department, Hospital Universitario de Salamanca, Salamanca, Spain; IBSAL, Centro de Investigacion del Cancer-IBMCC (USAL-CSIC), Salamanca

Nathan C. Bahr

University of Kansas Medical Center, Kansas City

Ziad Emarah

Oncology Center, Mansoura University, Mansoura, Egypt

Gina Varricchio

Azienda Ospedaliera Sant'Anna e San Sebastiano, Caserta

Milche Cvetanoski

University Clinic of Hematology, Skopje, North Macedonia

Ramon Garcia-Sanz

Hematology Department, Hospital Universitario de Salamanca, Salamanca

Mirjana Mitrovic

University Clinical Center Serbia, Medical Faculty University Belgrade, Belgrade, Serbia

Raphael Lievin

Hospital St Louis, Paris

Michaela Hanakova

Institute of Hematology and Blood Transfusion, Prague, Czech Republic

Zdeněk Račil

Institute of Hematology and Blood Transfusion, Prague, Czech Republic

Maria Vehreschild

Infektiologie, Universitatsklinikum Frankfurt am Main, Frankfurt am Main

Athanasios Tragiannidis

Aristotle University of Thessaloniki, Thessaloniki, Greece

Raquel Nunes Rodrigues

Portuguese Institute of Oncology, Lisbon

Daniel Garcia-Bordallo

Hospital Lucus Augusti, Lugo

Raul Cordoba

Fundacion Jimenez Diaz University Hospital, Health Research Institute IIS-FJD, Madrid

Alba Cabirta

Department of Hematology, Vall d’Hebron Hospital Universitari, Experimental Hematology, Vall d’Hebron Institute of Oncology (VHIO), Vall d’Hebron Barcelona Hospital Campus, Barcelona

Anna Nordlander

Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden

Emanuele Ammatuna

University Medical Center Groningen, Groningen

Elena Arellano

Department of Hematology, University Hospital Virgen Macarena - University Hospital Virgen del Rocio, Instituto de Biomedicina de Sevilla (IBIS / CSIC), Universidad de Sevilla, Seville

Dominik Wolf

Department of Hematology and Oncology, Medical University of Innsbruck, Innsbruck, Austria

Romane Prin

Centre Hospitalier d'Argenteuil, Argenteuil

Alessandro Limongelli

Ospedale San Martino, Genova

Martina Bavastro

Ospedale San Martino, Genova

Gokce Melis Colak

Department of Infectious Diseases and Clinical Microbiology, School of Medicine, Marmara University, Istanbul

Stefanie Grafe

University of Cologne, Faculty of Medicine and University Hospital Cologne, Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne

Ditte Stampe Hersby

Department of Hematology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark

Laman Rahimli

University of Cologne, Faculty of Medicine and University Hospital Cologne, Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne

Oliver A. Cornely

University of Cologne, Faculty of Medicine and University Hospital Cologne, Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne

Carolina Garcia-Vidal

Infectious Diseases Department, Hospital Clinic of Barcelona-IDIBAPS, Universitat de Barcelona, Barcelona, Spain; CIBERINFEC, Instituto de Salud Carlos III, Madrid

Livio Pagano

Hematology Unit, Fondazione Policlinico Universitario Agostino Gemelli - IRCCS, Rome

EPICOVIDEHA study group

Miloš Mladenović, ;Charlotte Flasshove, Bojana Mišković, ;José-María Ribera-Santasusana, Martin Hoenigl, Juergen Prattes, Malgorzata Mikulska, Annarosa Cuccaro, Emel Bekirova, Josip Batinić, ;Nick De Jonge, Tatjana Adžić-Vukičević, ;Ľuboš Drgoňa, Hans Martin Orth, Florian Reizine, Monica Piedimonte, Jörg Schubert, Andrés Soto-Silva, Jorge Loureiro-Amigo, Laura Serrano, Lisset Lorenzo De La Peña, Anna Guidetti, Irati Ormazabal-Vélez, Sandra Malak, Maria Calbacho, Noemí Fernández, Rafael F. Duarte, Elizabeth De Kort, Guldane Cengiz Seval, Luisa Verga, Rui Bergantim, María-Josefa Jiménez-Lorenzo, Johan Maertens, Nina Khanna, Matthias Egger, Omar-Francisco Coronel-Ayala, Przemyslaw Zdziarski, Alessandro Busca, Elena Busch, Christian Bjørn Poulsen, François Danion, Tania Cushion, Sergio Pinzón, Yung Gonzaga, Austin Kulasekararaj, Hossein Zarrinfar, Baerbel Hoell-Neugebauer, Chi Shan Kho, Rémy Duléry, Martin Kolditz, Monica Fung, Alina Daniela Tanase