Emerging Infectious Diseases (Oct 2023)

Influenza A(H5N1) Virus Infections in 2 Free-Ranging Black Bears (Ursus americanus), Quebec, Canada

  • Benjamin T. Jakobek,
  • Yohannes Berhane,
  • Marie-Soleil Nadeau,
  • Carissa Embury-Hyatt,
  • Oliver Lung,
  • Wanhong Xu,
  • Stéphane Lair

DOI
https://doi.org/10.3201/eid2910.230548
Journal volume & issue
Vol. 29, no. 10
pp. 2145 – 2149

Abstract

Read online

Wholly Eurasian highly pathogenic avian influenza H5N1 clade 2.3.4.4b virus was isolated from 2 free-ranging black bears with meningoencephalitis in Quebec, Canada. We found that isolates from both animals had the D701N mutation in the polymerase basic 2 gene, previously known to promote adaptation of H5N1 viruses to mammal hosts.

Keywords