Clinical Ophthalmology (Sep 2020)
Management Strategies of Ocular Chemical Burns: Current Perspectives
Abstract
Mohammad Soleimani, Morteza Naderan Ocular Trauma and Emergency Department, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, IranCorrespondence: Mohammad Soleimani; Morteza NaderanOcular Trauma and Emergency Department, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran 1336616351, IranTel +98 912 1096496Email [email protected]; [email protected]: Ocular chemical burns are absolute ophthalmic emergencies and require immediate management to minimize devastating sequelae. Management of alkali and acid burns is started at the scene of the accident by copious irrigation. Treatment is directed at improving epithelial integrity and stromal stability, reduction of undue inflammation, and prevention or timely management of complications. To ascertain the best possible outcome, numerous biological medications and surgical interventions have been merged into conventional therapeutic regimens. These include autologous and umbilical cord serum preparations, platelet-rich plasma, amniotic membrane transplantation, limbal stem-cell transplantation, and anti-angiogenic agents.Keywords: ocular chemical burn, amniotic membrane transplantation, autologous serum, limbal stem cell transplantation
