Nature Communications (Nov 2018)
Structural snapshot of a bacterial phytochrome in its functional intermediate state
- Andrea Schmidt,
- Luisa Sauthof,
- Michal Szczepek,
- Maria Fernandez Lopez,
- Francisco Velazquez Escobar,
- Bilal M. Qureshi,
- Norbert Michael,
- David Buhrke,
- Tammo Stevens,
- Dennis Kwiatkowski,
- David von Stetten,
- Maria Andrea Mroginski,
- Norbert Krauß,
- Tilman Lamparter,
- Peter Hildebrandt,
- Patrick Scheerer
Affiliations
- Andrea Schmidt
- Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal Transduction
- Luisa Sauthof
- Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal Transduction
- Michal Szczepek
- Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal Transduction
- Maria Fernandez Lopez
- Technische Universität Berlin, Institut für Chemie
- Francisco Velazquez Escobar
- Technische Universität Berlin, Institut für Chemie
- Bilal M. Qureshi
- Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal Transduction
- Norbert Michael
- Technische Universität Berlin, Institut für Chemie
- David Buhrke
- Technische Universität Berlin, Institut für Chemie
- Tammo Stevens
- Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal Transduction
- Dennis Kwiatkowski
- Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal Transduction
- David von Stetten
- Structural Biology Group, European Synchrotron Radiation Facility
- Maria Andrea Mroginski
- Technische Universität Berlin, Institut für Chemie
- Norbert Krauß
- Karlsruhe Institute of Technology (KIT), Botanical Institute
- Tilman Lamparter
- Karlsruhe Institute of Technology (KIT), Botanical Institute
- Peter Hildebrandt
- Technische Universität Berlin, Institut für Chemie
- Patrick Scheerer
- Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal Transduction
- DOI
- https://doi.org/10.1038/s41467-018-07392-7
- Journal volume & issue
-
Vol. 9,
no. 1
pp. 1 – 13
Abstract
Phytochromes are photoreceptors that are present in plants, bacteria and fungi. Here the authors present crystal structures of the phytochrome Agp2 from Agrobacterium fabrum in the parent Pfr state as well as a functional Meta-F intermediate and discuss mechanistic implications for photoconversion.
