Brazilian Neurosurgery (Dec 2022)

Recurrence of Anaplastic Large Cell Lymphoma in the Frontal Lobe After Eleven Years of the Initial Diagnosis: Histopathological Findings and Prognosis

  • Eduardo Cambruzzi,
  • Nelson Pires Ferreira,
  • Marcelo Paglioli Ferreira,
  • Guilherme Gago,
  • João Pedro Pattussi Bertinatti

DOI
https://doi.org/10.1055/s-0042-1749375
Journal volume & issue
Vol. 41, no. 04
pp. e375 – e378

Abstract

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Anaplastic large cell lymphoma (ALCL) is a rare, high-grade, T-cell neoplasm classified into cutaneous primary, systemic primary ALK-positive (ALK+), systemic primary ALK-negative, or breast-implant associated. Secondary involvement of the central nervous system (CNS) by systemic primary ALK+ ALCL is a rare occurrence. We present a case of CNS involvement by ALK+ ALCL eleven years after diagnosis of the primary tumor in the thoracic vertebra. The anatomopathological examination confirmed the diagnosis of ALK+ ALCL. A brief review of the treatment and the clinical and pathological aspects is presented.

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