Frontiers in Veterinary Science (Aug 2021)

Advanced Research in Porcine Reproductive and Respiratory Syndrome Virus Co-infection With Other Pathogens in Swine

  • Dengshuai Zhao,
  • Bo Yang,
  • Xingguo Yuan,
  • Chaochao Shen,
  • Dajun Zhang,
  • Xijuan Shi,
  • Ting Zhang,
  • Huimei Cui,
  • Jinke Yang,
  • Xuehui Chen,
  • Yu Hao,
  • Haixue Zheng,
  • Keshan Zhang,
  • Xiangtao Liu

DOI
https://doi.org/10.3389/fvets.2021.699561
Journal volume & issue
Vol. 8

Abstract

Read online

The porcine reproductive and respiratory syndrome virus (PRRSV) is the pathogen causing epidemics of porcine reproductive and respiratory syndrome (PRRS), and is present in every major swine-farming country in the world. Previous studies have demonstrated that PRRSV infection leads to a range of consequences, such as persistent infection, secondary infection, and co-infection, and is common among pigs in the field. In recent years, coinfection of PRRSV and other porcine pathogens has occurred often, making it more difficult to define and diagnose PRRSV-related diseases. The study of coinfections may be extremely suitable for the current prevention and control in the field. However, there is a limited understanding of coinfection. Therefore, in this review, we have focused on the epidemiology of PRRSV coinfection with other pathogens in swine, both in vivo and in vitro.

Keywords