Binary Titanium-tantalum alloys and their Biocompatibility

Abstract

The paper deals with investigation of biological properties of binary alloys of titanium with tantalum in relation to the ratio of mass share of tantalum in the alloy. Tests of cytocompatibility and genotoxicity have been made. The tests of cytocompatibility included those of cell growth, cell adherence, dilation test, tolerance test in monolayer, and in suspension. The genotoxicity tests encompassed those of induction of atypical mitoses, induction of chromosomal aberrations in a cell line and in human peripheral lymphocytes. Based of the evaluation of these biological tests the authors determined suitability of using such alloys in oral implantology. Beta alloys formed in this way can be recommended for use in the production of implants.

Keywords

• titanium
• tantalum
• binary beta alloys
• cytocompatibility
• genotoxicity