A unified deep-learning network to accurately segment insulin granules of different animal models imaged under different electron microscopy methodologies

• Xiaoya Zhang,
• Xiaohong Peng,
• Chengsheng Han,
• Wenzhen Zhu,
• Lisi Wei,
• Yulin Zhang,
• Yi Wang,
• Xiuqin Zhang,
• Hao Tang,
• Jianshe Zhang,
• Xiaojun Xu,
• Fengping Feng,
• Yanhong Xue,
• Erlin Yao,
• Guangming Tan,
• Tao Xu,
• Liangyi Chen

Affiliations

Xiaoya Zhang

State Key Laboratory of Membrane Biology, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University

Xiaohong Peng

State Key Laboratory of Membrane Biology, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University

Chengsheng Han

State Key Laboratory of Membrane Biology, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University

Wenzhen Zhu

State Key Laboratory of Membrane Biology, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University

Lisi Wei

State Key Laboratory of Membrane Biology, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University

Yulin Zhang

State Key Laboratory of Membrane Biology, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University

Yi Wang

State Key Laboratory of Membrane Biology, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University

Xiuqin Zhang

State Key Laboratory of Membrane Biology, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University

Hao Tang

University of Chinese Academy of Sciences

Jianshe Zhang

Marine Science College of Zhejiang Ocean University, National Engineering Research Center of Marine Facilities Aquaculture

Xiaojun Xu

National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences

Fengping Feng

National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences

Yanhong Xue

National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences

Erlin Yao

University of Chinese Academy of Sciences

Guangming Tan

University of Chinese Academy of Sciences

Tao Xu

National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences

Liangyi Chen

State Key Laboratory of Membrane Biology, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University