Journal of Ovarian Research (Aug 2011)

A retrospective analysis of clinicopathological and prognostic characteristics of ovarian tumors in the State of Espírito Santo, Brazil

  • Paes Marcela F,
  • Daltoé Renata D,
  • Madeira Klesia P,
  • Rezende Lucas CD,
  • Sirtoli Gabriela M,
  • Herlinger Alice L,
  • Souza Leticia S,
  • Coitinho Luciana B,
  • Silva Débora,
  • Cerri Murilo F,
  • Chiaradia Ana Cristina N,
  • Carvalho Alex A,
  • Silva Ian V,
  • Rangel Leticia BA

DOI
https://doi.org/10.1186/1757-2215-4-14
Journal volume & issue
Vol. 4, no. 1
p. 14

Abstract

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Abstract Background Ovarian cancer is sixth most common cancer among women and the leading cause of death in women with gynecological malignancies. Despite the great impact ovarian cancer has on women's health and its great impact in public economy, Brazil still lacks valuable information concerning epidemiological aspects of this disease Methods We've compiled clinical data of all ovarian tumors registered at the two public hospitals of reference (1997 - 2007), such as: patients' age at diagnosis, tumor histological type, tumor stage, chemotherapy regimens, chemotherapy responsiveness, disease-free survival, and overall survival. Results Women's mean age at diagnosis was 54.67 ± 13.84 for ovarian cancer, 46.15 ± 11.15 for borderline tumors, and 42.01 ± 15.06 for adenomas. Among epithelial ovarian cancer cases, 30.1% were of serous, 13.7% were of mucinous, and 13.7% were of endometrioid type; exceptionally serous carcinoma was diagnosed in women younger than 30 years old. Endometrioid cancer had lower disease-free survival than others (p Discussion Our data agreed with other studies regarding mean patients' age at diagnosis, histological type frequency, FIGO stages distribution, and chemotherapy regimens. However, the histological type distribution, with equal contribution of mucinous and endometrioid types seems to be a unique characteristic of the studied highly miscegenated population. Conclusion We have enlighten the profile of the studied ovarian cancer population, which might enable the development of more efficient political strategies to control this malignancy that is the fifth leading cause of cancer-related deaths among women.

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