Tomography (Jun 2023)

Visualization of Metastatic Lung Cancer with TiNIR

  • Seul-Ki Mun,
  • Hyun Bo Sim,
  • Ji Yeon Han,
  • Hyeongyeong Kim,
  • Dae-Han Park,
  • Dong-Jo Chang,
  • Sung-Tae Yee,
  • Young-Tae Chang,
  • Jong-Jin Kim

DOI
https://doi.org/10.3390/tomography9040096
Journal volume & issue
Vol. 9, no. 4
pp. 1187 – 1195

Abstract

Read online

The development of efficient biomarkers and probes for monitoring and treating cancer, specifically metastatic cancer, is a critical research area that can have a significant impact on both patient outcomes and drug discovery. In this context, TiNIR has been developed to detect tumor-initiating cells (TICs), with heme oxygenase 2 (HO2) as a promising therapeutic biomarker for tumor-initiating cells. In this study, TiNIR has demonstrated its effectiveness as an in vivo metastatic lung cancer tracker, highlighting its potential as a valuable tool in cancer research and therapy. The development of innovative approaches that selectively target metastatic cancers represents a promising avenue for improving survival rates and enhancing the quality of life of cancer patients.

Keywords