Lerisetron Analogues with Antimalarial Properties: Synthesis, Structure–Activity Relationship Studies, and Biological Assessment

• Rudolf Mueller,
• Virsinha Reddy,
• Aloysius T. Nchinda,
• Fanuel Mebrahtu,
• Dale Taylor,
• Nina Lawrence,
• Lloyd Tanner,
• Marine Barnabe,
• Charles J. Eyermann,
• Bin Zou,
• Ravinder R. Kondreddi,
• Suresh B. Lakshminarayana,
• Matthias Rottmann,
• Leslie J. Street,
• Kelly Chibale

Affiliations

Rudolf Mueller

Drug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Town, Rondebosch, South Africa

Virsinha Reddy

Drug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Town, Rondebosch, South Africa

Aloysius T. Nchinda

Drug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Town, Rondebosch, South Africa

Fanuel Mebrahtu

Drug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Town, Rondebosch, South Africa

Dale Taylor

Drug Discovery and Development Centre (H3D), Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Observatory, South Africa

Nina Lawrence

Drug Discovery and Development Centre (H3D), Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Observatory, South Africa

Lloyd Tanner

Drug Discovery and Development Centre (H3D), Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Observatory, South Africa

Marine Barnabe

Drug Discovery and Development Centre (H3D), Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Observatory, South Africa

Charles J. Eyermann

Drug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Town, Rondebosch, South Africa

Bin Zou

Shanghai Blueray Biopharma Co. LTD, Shanghai, China

Ravinder R. Kondreddi

PJS Pharma Pvt. Ltd., Hyderabad, India

Suresh B. Lakshminarayana

Novartis Institute for Tropical Diseases, Emeryville, California, United States

Matthias Rottmann

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland

Leslie J. Street

Drug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Town, Rondebosch, South Africa

Kelly Chibale

Drug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Town, Rondebosch, South Africa