Molecules (Oct 2014)

A Comprehensive Review of the Structure Elucidation and Biological Activity of Triterpenoids from Ganoderma spp.

  • Qing Xia,
  • Huazheng Zhang,
  • Xuefei Sun,
  • Haijuan Zhao,
  • Lingfang Wu,
  • Dan Zhu,
  • Guanghui Yang,
  • Yanyan Shao,
  • Xiaoxue Zhang,
  • Xin Mao,
  • Lanzhen Zhang,
  • Gaimei She

DOI
https://doi.org/10.3390/molecules191117478
Journal volume & issue
Vol. 19, no. 11
pp. 17478 – 17535

Abstract

Read online

Ganoderma triterpenes (GTs) are the major secondary metabolites of Ganoderma lucidum, a traditional Chinese medicine, popularly used for complementary cancer therapy. GTs are lanostane-tetracyclic triterpenes. They have been reported to possess anti-tumor, anti-inflammation, antioxidant, antimicrobial and blood fat reducing effects. To date, 316 GTs have been found and their similar chemical structures have proved difficult to elucidate. This paper compiles 316 naturally occurring triterpenes from Ganoderma based on the literature published through January 2013 along with their structures, physiological activities and 13C-NMR spectral data.

Keywords