Corresponding author.; Department of Dermatology and Venerology, Mohammed VI University Hospital, Av. Ibn Sina 2360, Bioscience and Health Laboratory, FMPM, Cadi Ayyad University, Marrakech, Morocco
Maryem Aboudourib
Department of Dermatology and Venerology, Mohammed VI University Hospital, Av. Ibn Sina 2360, Bioscience and Health Laboratory, FMPM, Cadi Ayyad University, Marrakech, Morocco
Ouafa Hocar
Department of Dermatology and Venerology, Mohammed VI University Hospital, Av. Ibn Sina 2360, Bioscience and Health Laboratory, FMPM, Cadi Ayyad University, Marrakech, Morocco
Said Amal
Department of Dermatology and Venerology, Mohammed VI University Hospital, Av. Ibn Sina 2360, Bioscience and Health Laboratory, FMPM, Cadi Ayyad University, Marrakech, Morocco
A 47-year-old, north african, male patient, has recently been diagnosed with pernicious anemia, treated with weekly intramuscular hydroxocobalamin. 6 weeks after its initiation, the patient presented a sudden, extensive and monomorphic eruption of inflammatory papulo-pustules and nodules, affecting the face, and the trunk. The eruption was pruritic, and comedones were also present, on the chest. The patient was diagnosed with vitamin B12-induced acneiform eruption. Levels of vitamin B12 were normalized. Hydroxocobalamin was therefore stopped and lymecycline was started, allowing a complete resolution of the lesions within 3 months. Drug intake, sudden and uncommon age of onset, pruritus, a monomorphic pattern and an involvement of extra-seborrheic areas are features that distinguish acneiform eruptions from acne vulgaris.
