Worsening of medication non-adherence among patients with chronic diseases during times of armed conflict in the war-torn region of Ethiopia

Abstract

Background: Armed conflict is a complex global phenomenon resulting in numerous injuries and significant health risks, particularly for individuals with chronic illness. This study aims to highlight the degree of medication non-adherence during armed conflict in northwest Ethiopia. Method: An institution-based cross-sectional study was conducted at comprehensive specialized hospitals in northwest Ethiopia. Proportional allocation was used to assign patients in each setting. Proportions and means were compared using the chi-square test and the t-test, respectively. Binary logistic regression was employed to identify significant factors. Results: The degree of medication non-adherence was 68.1 %, and 88.3 % of participants reported that the armed conflict had a negative impact on their treatment. Additionally, 69.1 % of participants claimed that they did not use strategies to cope with the challenges they faced. Significant factors associated with medication non-adherence included the absence of health insurance (AOR = 3.43 (95 % CI 2.04–5.76)), the presence of comorbid illness (AOR (95 % CI): 5.19 (2.91–9.24)), medication unavailability (AOR = 1.84 (95 % CI 1.02–3.30)), and routine follow-up disturbances (AOR = 2.03 (95 % CI 1.08–3.79)). Conclusion: Patients with chronic diseases exhibited a high rate of medication non-adherence during times of conflict. Particular attention should be given to patients with no social insurance, those with comorbid diseases, those experiencing follow-up disturbances, and those facing medication unavailability. Relevant entities are expected to develop initiatives that minimize constraints on medication adherence during armed conflicts.

Keywords

• Medication adherence
• Armed conflict
• Impact
• Chronic diseases
• Ethiopia