PLoS ONE (Jan 2024)

Relationship between body mass index and clinical events in patients with atrial fibrillation undergoing percutaneous coronary intervention.

  • Tatsuro Yamazaki,
  • Hideki Kitahara,
  • Daichi Yamashita,
  • Takanori Sato,
  • Sakuramaru Suzuki,
  • Takashi Hiraga,
  • Tadahiro Matsumoto,
  • Takahiro Kobayashi,
  • Yuji Ohno,
  • Junya Harada,
  • Kenichi Fukushima,
  • Tatsuhiko Asano,
  • Naoki Ishio,
  • Raita Uchiyama,
  • Hirofumi Miyahara,
  • Shinichi Okino,
  • Masanori Sano,
  • Nehiro Kuriyama,
  • Masashi Yamamoto,
  • Naoya Sakamoto,
  • Junji Kanda,
  • Yoshio Kobayashi

DOI
https://doi.org/10.1371/journal.pone.0309758
Journal volume & issue
Vol. 19, no. 9
p. e0309758

Abstract

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BackgroundIt is still unclear whether body mass index (BMI) affects bleeding and cardiovascular events in patients requiring oral anticoagulants (OAC) for atrial fibrillation (AF) and antiplatelet agents after percutaneous coronary intervention (PCI) for coronary artery disease (CAD). The aim of this study was to evaluate the relationship between BMI and clinical events in patients who underwent PCI under OAC therapy for AF.MethodThis was a multicenter, observational cohort study conducted at 15 institutions in Japan. AF patients who underwent PCI with drug-eluting stents for CAD were retrospectively and prospectively included. Patients were divided into the Group 1 (BMI ResultsIn the 720 patients, 180 patients (25.0%) had BMI value ConclusionsAmong the patients undergoing PCI for CAD and requiring OAC for AF, BMI value was a useful indicator to predict major adverse clinical events.