Semina: Ciências Agrárias (Feb 2015)

Identification of the presence of the mutation of the gene of PKD not associated with mutation of MYBPC3-A31P of HCM in Persian cats – Case Report

  • Vanesa Kutz de Arruda ,
  • Mariana Isa Poci Palumbo ,
  • Priscilla Macedo de Souza,
  • José Paes Oliveira-Filho,
  • Alexandre Secorun Borges ,
  • Maria Lucia Gomes Lourenço

DOI
https://doi.org/10.5433/1679-0359.2015v36n1p301
Journal volume & issue
Vol. 36, no. 1
pp. 301 – 306

Abstract

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Polycystic kidney disease (PKD) is a hereditary autosomal dominant disorder that mainly affects Persian cats; it is an important cause of chronic kidney disease in this species. Hypertrophic cardiomyopathy (HCM) is the most common heart disease in cats, and there is evidence of a genetic origin in some breeds. Although neither of these disorders is rare in cats, according to our literature review, this is the first report of the concomitant occurrence of PKD and HCM in Persian cats in Brazil.

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