Perineuronal nets stabilize the grid cell network

Ane Charlotte Christensen; Kristian Kinden Lensjø; Mikkel Elle Lepperød; Svenn-Arne Dragly; Halvard Sutterud; Jan Sigurd Blackstad; Marianne Fyhn; Torkel Hafting

doi:10.1038/s41467-020-20241-w

Nature Communications (Jan 2021)

Affiliations

Ane Charlotte Christensen: Institute of Basic Medical Sciences, University of Oslo
Kristian Kinden Lensjø: Department of Biosciences, University of Oslo
Mikkel Elle Lepperød: Institute of Basic Medical Sciences, University of Oslo
Svenn-Arne Dragly: Center for Integrative Neuroplasticity, University of Oslo
Halvard Sutterud: Center for Integrative Neuroplasticity, University of Oslo
Jan Sigurd Blackstad: Department of Biosciences, University of Oslo
Marianne Fyhn: Department of Biosciences, University of Oslo
Torkel Hafting: Institute of Basic Medical Sciences, University of Oslo

DOI: https://doi.org/10.1038/s41467-020-20241-w
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 17

Abstract

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Perineuronal nets may stabilize synaptic connections. Here, the authors show that removal of perineuronal nets disrupts both the temporal and spatial organization of grid cell firing.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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