Successful therapy of Candida pulcherrima fungemia in a premature newborn with liposomal amphotericin B and micafungin

Abstract

New Candida species may cause bloodstream infections challenging current therapeutic approaches because of unpredictable susceptibility and virulence. In the present report, we describe a fungemia case due to Candida pulcherrima in a premature neonate. After full in vitro diagnostic workup, the neonate was successfully treated with liposomal amphotericin B and micafungin achieving rapid fungal eradication from blood.

Keywords

• Candidemia
• Neonate
• Combination antifungal therapy
• Micafungin
• Liposomal amphotericin B