Successful autologous stem cell transplantation for light chain proximal tubulopathy with severe kidney injury

Abstract

Key Clinical Message Light chain proximal tubulopathy (LCPT) is a rare type of monoclonal gammopathy of renal significance. Clinicians should consider LCPT in the differential diagnosis of patients with renal or proximal tubular dysfunction with monoclonal gammopathy. They should confirm diagnosis by renal biopsy and initiate chemotherapy before disease progression.

Keywords

• Fanconi syndrome
• hematopoietic stem cell transplantation
• monoclonal Gammopathy of undetermined significance
• multiple myeloma
• proximal renal tubular dysfunction