Future Science OA (Dec 2020)

Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data

  • Nina J Karlin,
  • Matthew R Buras,
  • Heidi E Kosiorek,
  • Kyle E Coppola,
  • Patricia M Verona,
  • Curtiss B Cook

DOI
https://doi.org/10.2144/fsoa-2020-0055
Journal volume & issue
Vol. 6, no. 10

Abstract

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Aim: To evaluate overall survival (OS), glycemic control in cancer patients with and without diabetes mellitus (DM). Patients & methods: Patients (2010–2015) with newly diagnosed prostate, breast, lung, colorectal and pancreatic cancers were identified in institutional cancer registry. Data linked to National Death Index for vital status. 5-year OS estimated; glucose and hemoglobin A1c assessed during year postdiagnosis. Results: We identified 1404 patients (non-DM, n = 936; DM, n = 468). DM cohort had 168 deaths (36%); non-DM, 267 (29%). 5-year OS estimated at 58% (95% CI: 53–64%) for DM and 67% (95% CI: 64–71%) for controls; for matched pairs, hazard ratio: 1.35 (95% CI: 1.02–1.79). Cancer did not harm glycemic control. Conclusion: OS among cancer patients with DM was lower than without DM.

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