Zhongguo quanke yixue (May 2022)

Latest Advances in Coping Modes for Potentially Inappropriate Medications in Older Adults

  • Simeng WANG, Chen ZHANG, Xue SUN, Lina WANG

DOI
https://doi.org/10.12114/j.issn.1007-9572.2022.0077
Journal volume & issue
Vol. 25, no. 13
pp. 1551 – 1556

Abstract

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Due to susceptibility to multiple chronic diseases, polypharmacy is often needed in older adults, which may easily lead to increased risk of potentially inappropriate medications (PIM) if polypharmacy is accompanied by various alterations in pharmacokinetics and pharmacodynamics of medications. PIM are highly prevalent in older adults, which may be asociated with higher risks of frailty, falls, cognitive decline, and other adverse drug events. In China, the research on PIM is relatively weak, and PIM are insufficiently focused and often managed with non-standardized and non-intelligent approaches in primary care. We systematically reviewed recent studies in the prevalence, screening and assessment tools and management strategies of PIM in older adults, providing theoretical support and practical reference for reducing the harm of PIM and standardizing drug management.

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