Quality of Life in Adult Patients Treated with Peripheral Blood Progenitor Cell Transplantation: the Effect of Selected Psychosocial, Demographics and Health Aspects on Quality of Life: a Retrospective Analysis

Abstract

Aim: this retrospective study analyses the effect of selected psychosocial, demographics and health aspects on quality of life (QoL) in adult patients treated with peripheral blood progenitor cell transplantation (PBPCT). Patients and Methods: The total number of respondents treated with PBPCT between the years 2001–2003 was 95. The return rate of QoL questionnaires was 72.1 % (71 respondents). There were 100 % ratable QoL questionnaire. The average age of all respondents was 55.5 years old. The Czech version of an international generic European Quality of Life Questionnaire – Version EQ-5D was used. The effect of selected aspects on QoL of patients was determined by analysis of variance. The QoL questionnaires were evaluated with descriptive analysis. Results: The above-mentioned aspects proved statistically significant dependence of QoL (EQ-5D score – QoL dimensions, EQ-5D VAS – subjective health condition) on age, increasing number of associated diseases, religion and type of disease. The effect of other aspects on QoL was not proven statistically significant. The QoL in adult patients treated with PBPCT declines with increasing age and with the increasing number of associated diseases. People of faith have a higher level of QoL than non-believers. Patients with multiple myeloma treated with PBPCT have the most low QoL. Conclusion: The global QoL in an adult patients treated with PBPCT is on a good level.

Keywords

• Quality of life
• Peripheral blood progenitor
• Cell transplantation
• Quality of life questionnaires