Indian Journal of Pathology and Microbiology (Jan 2022)

Angiomatoid fibrous histiocytoma: Report of two cases, initially construed as sarcoma with unusual clinico-pathological features

  • Sunil Pasricha,
  • Garima Durga,
  • Anila Sharma,
  • Manish Pruthi,
  • Meenakshi Kamboj,
  • Gurudutt Gupta,
  • Ankush Jajodia,
  • Vivek Mahawar,
  • Venkata Pradeep Babu Koyyala,
  • Anurag Mehta

DOI
https://doi.org/10.4103/ijpm.ijpm_1468_20
Journal volume & issue
Vol. 65, no. 4
pp. 921 – 924

Abstract

Read online

Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor of uncertain differentiation with low metastatic potential, most commonly occurring in children, adolescents, and young adults, involving extremities. Due to its rare nature and diverse presentation, both clinically and morphologically, it is often misdiagnosed. It becomes important to correctly diagnose this lesion, given its distinct therapeutic implications. Here, we present the clinical, radiologic, and pathologic findings of two rare cases of AFH. Since AFH is a rare soft tissue tumor with low malignant potential, both pathologists and clinicians should be aware of this entity, when encountered with a soft tissue mass in extremities of a child or adolescent, so as to accord appropriate treatment in such cases.

Keywords