S253: THE SHEDDASE DOMAIN OF ADAM10 AUGMENTS THE INTERACTION OF LEUKEMIA CELLS WITH THE BONE MARROW NICHE IN VIVO AS SHOWN BY RECONSTITUTING PDX LEUKEMIA CELLS WITH CRISPR-CAS9-INDUCED KNOCKOUT
J. P. Schmid,
E. Bahrami,
M. Becker,
A. K. Jayavelu,
A.-K. Wirth,
V. Jurinovic,
R. Öllinger,
R Rad,
B. Vick,
M. Mann,
T. Herold,
I. Jeremias
Affiliations
J. P. Schmid
1 Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU)
E. Bahrami
1 Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU)
M. Becker
1 Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU)
A. K. Jayavelu
3 Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried
A.-K. Wirth
1 Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU)
V. Jurinovic
1 Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU)
R. Öllinger
6 Center for Translational Cancer Research (TranslaTUM), TUM School of Medicine, Technische Universität München
R Rad
2 German Cancer Consortium (DKTK), partner site Munich, Munich
B. Vick
1 Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU)
M. Mann
3 Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried
T. Herold
1 Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU)
I. Jeremias
1 Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU)
