Communications Biology (Jan 2021)
Obese mother offspring have hepatic lipidic modulation that contributes to sex-dependent metabolic adaptation later in life
Abstract
Savva et al. investigate the sex dependent effect of maternal obesity on the metabolism of offspring. They find that metabolic changes are conferred on a sex basis, with males suffering from impaired lipid metabolism relative to females when born to obese mothers, using a lipidomic approach.