A Xanthan‐Gum‐Stabilized PEG‐Conjugated Nanocurcumin Complex: Telescoping Synthesis for Enhanced Permeation Potential

Abstract

Abstract We report a facile room temperature telescoping synthesis of a nanocurcumin complex with 17.5‐fold permeation enhancement as determined by comparative in vitro permeation study with raw curcumin. The permeation results were further validated with in silico drug absorption prediction using ADMET predictors.

Keywords

• DFT simulation
• nanocurcumin
• PEG conjugation
• permeation potential
• telescoping synthesis