Comparative characteristic of methods for determining the inflammation marker matrix metalloproteinase-9

Abstract

Aim. We examined 88 patients with stroke, for whom the determination of the concentration of matrix metalloproteinase-9 (MMP-9) in serum was carried out by standard methods declared in instructions supplied with the reagents kit, and by the modified methods. Results. It was determined that the modified methods of determining the MMP-9 can be used in predicting the occurrence of secondary hemorrhagic complications and to determine the feasibility and safety of thrombolytic therapy. Conclusion. If the concentration of MMP-9 by the modified methods of determining is below 39,7 ng/ml, the percentage of secondary hemorrhagic complications is minimal.

Keywords

• Stroke
• Matrix Metalloproteinase-9