CURRENT PROBLEMS OF EPIDEMIOLOGY, DIAGNOSIS AND TREATMENT OF COMPLICATIONS OF UROLITHIASIS

Abstract

The question of studying the characteristics of sensitivity / resistance of bacteria isolated from patients with urolithiasis in order to develop optimal therapy and correct complications in patients with a urological profile is relevant. Purpose of the study. Study of the etiological structure and level of antibiotic resistance of pathogens of infectious and inflammatory complications of infections in patients with a urological profile. Methods. The case histories of 345 patients who were treated in the urology department with a diagnosis of urolithiasis, male and female over the age of 18, were studied. The material for bacteriological studies was urine. Results. When analyzing age indicators, it was found that adults over the age of 31-40 years are more likely to be at risk of developing the studied infections. Infectious and inflammatory complications were presented: acute pyelonephritis, acute cystitis. The spectrum of pathogens of infectious and inflammatory complications of the urinary tract in patients after long-distance lithotripsy is mainly represented by gram-negative flora: E. coli, Ps. aeruginosa, Proteus spp. Staphylococcus sapr prevailed among representatives of gram-positive pathogens. The most effective drugs against Ps strains. Aeruginosa proved to be polymyxin, cephalexin. Almost all Klebsiella strains showed high sensitivity to cephalotin and cephalexin. Microorganisms of the genus Proteus showed high sensitivity to gentamicin and cephalexin. Ñonclusion. It is advisable to use the data when choosing the starting empirical antibiotic therapy in the development of the leading complications of distant lithotripsy.

Keywords

• lithotripsy
• urinary tract infections
• pathogens
• antibiotic resistance.